MS-N120 · Supportive care · Human evidence · Appraised 24 October 2026
After laparoscopic colorectal cancer surgery within an enhanced-recovery pathway, can electroacupuncture shorten postoperative ileus?
Evidence at a glance
- Evidence label: Promising perioperative evidence; not yet routine care
- Benefit: A multicenter sham-controlled trial found earlier first defecation and fewer cases of prolonged postoperative ileus.
- Certainty: Moderate confidence in the measured short-term effect; replication outside the studied surgical system is needed.
- Risk: No severe treatment-related adverse events were reported, but perioperative needling requires surgical-team coordination.
What was studied
Population and design: 249 adults were randomized at three Chinese hospitals; 248 were analyzed after laparoscopic colorectal cancer resection.
Studied regimen: Four electroacupuncture sessions after surgery versus sham electroacupuncture, alongside the same enhanced recovery protocol.
What the evidence found
Median time to first defecation was 76.4 hours with electroacupuncture versus 90.0 hours with sham. The adjusted mean difference was −8.76 hours (95% CI −15.80 to −1.73; P=.003). Prolonged postoperative ileus occurred in 10% versus 20% (risk ratio 0.51, 95% CI 0.27–0.95). Several other secondary recovery outcomes did not differ.
How to interpret it
The absolute gain was measured in hours and its practical importance will vary. The trial was conducted in China with protocolized surgery and acupuncture; it does not establish effects on complications beyond ileus, readmission, tumor control or survival.
Practical safety context
No severe acupuncture-related adverse events were reported. Needling soon after surgery should be discussed with the surgeon, especially with bleeding risk, infection, drains, altered anatomy or unstable cardiopulmonary status. It should never delay evaluation of obstruction, leak or other surgical complications.
Questions for the care team
- Is the symptom or complication being caused by something that needs conventional treatment first?
- Would blood counts, anticoagulants, infection risk, surgery, radiation effects or implanted devices change whether this is safe?
- What outcome will we track, and when should we stop if it is not helping?
Funding and conflicts
Chinese public research funding was reported; detailed funder roles and author conflicts are available in the full report.
Sources
- Primary RCT: JAMA Surgery (PMID 36322060; PMCID PMC9631228)
- Full text
- Registry: ChiCTR2000038444
- DOI 10.1001/jamasurg.2022.5674
- Earlier three-arm trial (PMID 23142625)
Last literature search: 24 October 2026. Record appraisal: 24 October 2026. This page is educational and does not replace individualized medical advice. Symptom improvement must not be interpreted as evidence of tumor response, delayed recurrence or longer survival.