Missing ScriptStart HereBlogCountry ExplorerIntegrative Care GuideEvidence ExplorerPodcastAbout

Evidence Explorer / Evidence record

BOTANICALS & NATURAL PRODUCTS

Mistletoe extracts

Uncertain evidence

Some reports describe quality-of-life or survival benefits, but major study weaknesses limit confidence.

MS-N004 · Sources checked October 11, 2026 · Quality of life and cancer-control claims

What was studied?

People and setting: Multiple cancer settings; specific injectable extracts

Evidence basis: Heterogeneous clinical studies summarized by NCI

What can we conclude?

NCI’s review does not support use outside well-designed clinical trials. Preparations and outcomes differ.

Safety and practical context

Injection reactions and allergy are concerns. Do not ingest raw mistletoe or berries; they can be poisonous.

Questions for the care team

  • Does this evidence apply to my cancer, treatment and goal?
  • Does the exact preparation or delivery method match the study?
  • What benefit is plausible, what could go wrong, and what care must continue?

Sources

Connected reviews

Learn how to judge a study · Return to the evidence map

This is a concise evidence brief, not an exhaustive systematic review or a personal treatment recommendation. Evidence labels describe the named use; they are not formal GRADE ratings. A missing harm report does not establish safety.